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The following laboratory tests have been found to be abnormal in a few patients receiving Lioresalincreased SGOTelevated alkaline phosphataseand elevation of blood sugar.

Because LIORESAL is primarily excreted unchanged by the kidneysit should be given with caution in patients with impaired renal function and it may be necessary to reduce the dosage.

Baclofen is used to treat muscle spasms caused by certain conditionssuch as multiple sclerosisspinal cord injury/diseaseIt works by helping to relax the muscles.

This medication has been prescribed for your current condition onlyDo not use it later for another condition unless your doctor directs you to do soA different medication may be necessary in that case.

LIORESAL INTRATHECALbaclofen injectionis indicated for use in the management of severe spasticityPatients should first respond to a screening dose of intrathecal baclofen prior to consideration for long term infusion via an implantable pumpFor spasticity of spinal cord originchronic infusion of LIORESAL INTRATHECAL via an implantable pump should be reserved for patients unresponsive to oral baclofen therapyor those who experience intolerable CNS side effects at effective dosesPatients with spasticity due to traumatic brain injury should wait at least one year after the injury before consideration of long term intrathecal baclofen therapyLIORESAL INTRATHECAL is intended for use by the intrathecal route in single bolus test dosesvia spinal catheter or lumbar punctureandfor chronic useonly in implantable pumps approved by the FDA specifically for the administration of LIORESAL INTRATHECAL into the intrathecal space.

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